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Clinical Trials

Latest updates on clinical trials and their results.

Articles

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PulseSight Therapeutics closes Series A financing for dry AMD phase 1 clinical study

Ophthalmology biotech PulseSight Therapeutics has confirmed the closure of its Series A funding round, the proceeds of which will be used to fund a phase 1 study into its dry age-related macular degeneration (AMD) therapy, PST-611. The funding round was supported by existing investor Pureos BioVentures.

13 March 2025Clinical Trials
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Emalex Bioscience’s candidate for Tourette syndrome meets phase 3 endpoints

Paragon Bioscience’s clinical biopharma spin-out, Emalex Bioscience, has announced that its lead candidate for the treatment of Tourette syndrome has met its primary and secondary endpoints in a recent phase 3 study.

13 March 2025Clinical Trials
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Recce Pharmaceuticals reports positive phase 2 data for skin infection drug

Recce Pharmaceuticals has announced positive patient data from its phase 2 clinical trial into RECCE 327 (R327), for the treatment of acute bacterial skin and skin structure infections (ABSSSIs), including diabetic foot infections (DFI).

13 March 2025Clinical Trials
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Data shows long-term success for biosimilar switch in IBD

Real-world data into a mandatory non-medical switching policy for patients with inflammatory bowel disease (IBD) has shown long-term safety and efficacy. The patients transitioned from using adalimumab (Humira) to a biosimilar due to the enaction of the policy in British Columbia, Canada – the first Canadian province to do so.

13 March 2025Clinical Trials
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€7m financing announced to further clinical trials in thrombo-inflammatory diseases

Aplagon, a clinical stage biopharmaceutical company dedicated to the development of first-in-class therapeutics for thrombo-inflammatory diseases, has announced the closing of a €7m financing round for the initiation of phase 2a of its clinical trials.

12 February 2025Clinical Trials
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AnaCardio raises $19m in funding round for heart failure candidate

Swedish biopharmaceutical company AnaCardio has announced the completion of a Series A extension financing round that has raised $19m for its novel contractile agents. The round was co-led by Novo Holdings, Pureos Bioventures and Sound Bioventures.

12 February 2025Clinical Trials
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Positive topline results announced in phase 2 alcohol use disorder study

Beckley Psytech Ltd, a clinical-stage biopharmaceutical company that specialises in the production of accessible medicines for mental health conditions, has announced positive results for the phase 2a study into BPL-003 in patients with moderate-to-severe alcohol use disorder (AUD).

12 February 2025Clinical Trials
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Results from Novadip phase 1b/2a trial reveal 88% efficacy

Novadip Biosciences, a clinical stage biotechnology company with a specialty in regenerative medicine, has announced the results of its 12-month post-surgical visit as part of phase 1b/2a of the NCT05693558 trial.

12 February 2025Clinical Trials
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AdipoPharma secures funding for clinical trial into its insulin resistance compound

French biotech AdipoPharma has announced that it has secured funding for a clinical trial into its type 2 diabetes therapeutic, PATAS.

6 December 2024Clinical Trials
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GSK’s linerixibat shows positive phase 3 results for cholestatic pruritus in PBC

Global biopharma company GSK has announced positive phase 3 results for its cholestatic pruritus (relentless itch) in primary biliary cholangitis (PBC) treatment, linerixibat, which is currently being studied in the GLISTEN trial.

6 December 2024Clinical Trials
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Puma Biotechnology initiates phase 2 trial for breast cancer drug

Puma Biotechnology has announced the initiation of its alisertib in cancer (ALISCATM-Breast1) phase 2 trial of alisertib in combination with endocrine therapy. Based on the outcomes of the trial, the company anticipates to meet with the US Food and Drug Administration (FDA) regarding an approval pathway.

6 December 2024Clinical Trials
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Phase 2b results announced by Barinthus Biotherapeutics for HBV003 trial

UK-based Barinthus Biotherapeutics has announced data from its ongoing phase 2b HBV003 clinical trial, which was presented at the American Association for the Study of Liver Diseases (AASLD) Meeting 2024.

6 December 2024Clinical Trials