Contents

Stefan Woxström at AstraZeneca tells Pharmafocus about the link between climate change and human health

Prof Shai Shen-Orr at CytoReason explores the need for patient heterogeneity and why this is so central to successful drug development

Fiona Maini from Medidata speaks about pharmaceutical regulation and the opportunities and challenges of digitalisation and a rapidly evolving industry

Betsy Goodfellow considers the effects of climate change and how this could worsen, or even trigger, future pandemics

Page 4 – FDA issues update around changes to COVID-19 vaccines’ EUAs

Page 6 – Eli Lilly shares positive results from phase 3 study of donanemab for early Alzheimer’s disease

Page 7 – Merck’s relapsing multiple sclerosis trial put on FDA partial clinical hold over liver injuries

Page 9 – NICE recommends two CAR T treatments for blood cancers to the Cancer Drugs Fund

Page 10 – 3B Pharmaceuticals and Novartis enter into licensing agreement for FAP-targeting technology

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